Identifying Genetic Signatures Associated with Oncogene-Induced Replication Stress in Osteosarcoma and Screening for Potential Targeted Drugs
M Gao, W Liu, T Li, ZL Song, XY Wang, XS Zhang - Biochemical Genetics, 2024 - Springer
Osteosarcoma is the most common type of primary malignant bone tumor. Due to the lack of
selectivity and sensitivity of chemotherapy drugs to tumor cells, coupled with the use of large …
selectivity and sensitivity of chemotherapy drugs to tumor cells, coupled with the use of large …
[HTML][HTML] Molecular Analysis of Murine KitK641E Melanoma Progression
Acral and mucosal melanomas are often driven by sequence variants in the KIT receptor
tyrosine kinase, with nearly 40% harboring alterations in the KIT locus. Despite advances in …
tyrosine kinase, with nearly 40% harboring alterations in the KIT locus. Despite advances in …
Causes, consequences and clinical significance of aneuploidy across melanoma subtypes
Aneuploidy, the state of the cell in which the number of whole chromosomes or chromosome
arms becomes imbalanced, has been recognized as playing a pivotal role in tumor evolution …
arms becomes imbalanced, has been recognized as playing a pivotal role in tumor evolution …