The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Hypertrophic cardiomyopathy is the most common genetic heart disease. Biomarkers,
molecules measurable in the blood, could inform the clinician by aiding in diagnosis …

Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Geroscience puts mechanisms of aging as a driver of the most common age-related
diseases and dysfunctions. Under this perspective, addressing the basic mechanisms of …

The term “inflammageing” was introduced in 2000, with the aim of describing the chronic
inflammatory state typical of elderly individuals, which is characterized by a combination of …

Cell communication is needed for organ function and stress responses, especially in the
heart. Cardiac fibroblasts, cardiomyocytes, immune cells and endothelial cells comprise the …

Cardiac fibrosis constitutes irreversible necrosis of the heart muscle as a consequence of
different acute (myocardial infarction) or chronic (diabetes, hypertension,…) diseases but …

Simple Summary Breast cancer is the most frequently diagnosed cancer in women, causing
over 500,000 deaths worldwide. Human epidermal growth factor receptor 2 is …

Timely prediction of the risk of heart failure in acute myocardial infarction patients is critical
for better prognosis. This article aims to evaluate the predictive value of serum soluble …

Increased left ventricular fibrosis has been reported in patients hospitalized with coronavirus
disease 2019 (COVID-19). It is unclear whether this fibrosis is a consequence of severe …