G protein–coupled receptors (GPCRs) continue to be important discovery targets for the
treatment of type 2 diabetes mellitus (T2DM). Many GPCRs are directly involved in the …

RNA interference (RNAi) is a robust gene silencing mechanism that degrades mRNAs
complementary to the antisense strands of double-stranded, short interfering RNAs …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
39690775&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Results: As an outcome the search for a prodrug or mutual prodrug with reduced toxicity has
continued during recent years. This present review emphasizes the common help to revamp …

The therapy of various diseases by the drugs entrapped in calixarene derivatives is gaining
attraction of researchers nowadays. Calixarenes are macrocyclic nano-baskets which …

Modified glucagon peptides are disclosed having improved solubility and/or half-life while
retaining glucagon agonist activity. The glycogen peptides have been modified by Sub …

The discoveries of the incretin hormone glucagon‐like peptide‐1 (GLP‐1) and the β‐cell
hormone amylin have translated into hormone‐based therapies for diabetes. Both classes of …

Acinetobacter baumannii is a gram-negative bacterium causing severe hospital-acquired
infections such as bloodstream infections or pneumonia. Moreover, multidrug resistant A …

This article emphasizes the importance of prodrugs and their diverse spectrum of effects in
the field of developing novel drugs for a variety of biological applications. Prodrugs are …

4,275,152 A 6/1981 Esders et al. 5,359,030 A 10/1994 Ekwuribe(57) ABSTRACT 5,510,459
A 4/1996 Smith et al. 5,512,549 A 4/1996 Chen et a1. Modi? ed glucagon peptides are …