The potential of DNA methylation as a biomarker for obesity and smoking

A Heikkinen, S Bollepalli… - Journal of internal …, 2022 - Wiley Online Library
DNA methylation is an epigenetic modification that has consistently been shown to be linked
with a variety of human traits and diseases. Because DNA methylation is dynamic and …

Perspectives and challenges of epigenetic determinants of childhood obesity: a systematic review

R Alfano, O Robinson, E Handakas, TS Nawrot… - Obesity …, 2022 - Wiley Online Library
The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

Epigenetics as a biomarker for early-life environmental exposure

R Schrott, A Song, C Ladd-Acosta - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …

What role does the endocannabinoid system play in the pathogenesis of obesity?

P Schulz, S Hryhorowicz, AM Rychter, A Zawada… - Nutrients, 2021 - mdpi.com
The endocannabinoid system (ECS) is an endogenous signaling system formed by specific
receptors (cannabinoid type 1 and type 2 (CB1 and CB2)), their endogenous ligands …

Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and …

CC Onyekweli, B Ben-Azu, OM Oyovwi… - Food and Chemical …, 2024 - Elsevier
This study investigated whether epigallocatechin-gallate (EGCG) could counteract the
detrimental effects of high-fat diet (HFD)-induced obesity in rats exposed to rapamycin …

Precision nutrition: recent advances in obesity

VS Voruganti - Physiology, 2023 - journals.physiology.org
“Precision nutrition” is an emerging area of nutrition research that focuses on understanding
metabolic variability within and between individuals and helps develop customized dietary …

Emerging role of epigenetics in explaining relationship of periodontitis and cardiovascular diseases

SA Hamza, S Asif, Z Khurshid, MS Zafar, SAH Bokhari - Diseases, 2021 - mdpi.com
Cardiovascular diseases such as ischemic heart diseases or stroke are among the leading
cause of deaths globally, and evidence suggests that these diseases are modulated by a …

Panoramic on epigenetics in coronary artery disease and the approach of personalized medicine

M Bergonzini, F Loreni, A Lio, M Russo, G Saitto… - Biomedicines, 2023 - mdpi.com
Epigenetic modifications play a fundamental role in the progression of coronary artery
disease (CAD). This panoramic review aims to provide an overview of the current …

Elucidation of epigenetic landscape in coronary artery disease: a review on basic concept to personalized medicine

MP Sumi, B Mahajan, RSA Sattar, Nimisha… - Epigenetics …, 2021 - journals.sagepub.com
Despite extensive clinical research and management protocols applied in the field of
coronary artery diseases (CAD), it still holds the number 1 position in mortality worldwide …

Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation

Q Xu, L Zhou, H Ri, X Li, X Zhang, W Qi, L Ye - Environmental Toxicology …, 2022 - Elsevier
Abstract Mono (2-ethylhexyl) phthalate (MEHP) can influence the expression of estrogen
receptors (ERs) and induce thyroid injury. The expression of ERs can be related to thyroid …