[PDF][PDF] gamma-H2AX as protein biomarker for radiation exposure

K Rothkamm, S Horn - Ann Ist Super Sanita, 2009 - Citeseer
For large scale exposures of the human population to ionising radiation, there is a need for
cost-effective high throughput assessment of radiation exposure levels from biological …

Factors to consider for the correct use of γH2AX in the evaluation of DNA double-strand breaks damage caused by ionizing radiation

D Valente, MP Gentileschi, A Guerrisi, V Bruzzaniti… - Cancers, 2022 - mdpi.com
Simple Summary The increase of exposure to ionizing radiation (IR) from medical
procedures has prompted research into improving methodologies for the detection of DNA …

Assessment of biodosimetry methods for a mass-casualty radiological incident: medical response and management considerations

JM Sullivan, PGS Prasanna, MB Grace… - Health …, 2013 - journals.lww.com
Following a mass-casualty nuclear disaster, effective medical triage has the potential to save
tens of thousands of lives. In order to best use the available scarce resources, there is an …

Development of gene expression signatures for practical radiation biodosimetry

S Paul, SA Amundson - … Journal of Radiation Oncology* Biology* Physics, 2008 - Elsevier
PURPOSE: In a large-scale radiologic emergency, estimates of exposure doses and
radiation injury would be required for individuals without physical dosimeters. Current …

Gene expression following ionising radiation: identification of biomarkers for dose estimation and prediction of individual response

S Kabacik, A Mackay, N Tamber… - … journal of radiation …, 2011 - Taylor & Francis
Purpose: To establish a panel of highly radiation responsive genes suitable for biological
dosimetry and to explore inter-individual variation in response to ionising radiation …

Retrospective and emergency dosimetry in response to radiological incidents and nuclear mass-casualty events: a review

IK Bailiff, S Sholom, SWS McKeever - Radiation Measurements, 2016 - Elsevier
This paper reviews recent research on the application of the physical dosimetry techniques
of electron paramagnetic resonance (EPR) and luminescence (optically stimulated …

BiodosEPR-2006 Meeting: Acute dosimetry consensus committee recommendations on biodosimetry applications in events involving uses of radiation by terrorists …

GA Alexander, HM Swartz, SA Amundson… - Radiation …, 2007 - Elsevier
In the aftermath of a radiological terrorism incident or mass-casualty radiation accident, first
responders and receivers require prior guidance and pre-positioned resources for …

Comparison of established and emerging biodosimetry assays

K Rothkamm, C Beinke, H Romm… - Radiation …, 2013 - meridian.allenpress.com
Rapid biodosimetry tools are required to assist with triage in the case of a large-scale
radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well …

High and low dose responses of transcriptional biomarkers in ex vivo X-irradiated human blood

G Manning, S Kabacik, P Finnon… - International journal of …, 2013 - Taylor & Francis
Purpose: Modifications of gene expression following ionizing radiation (IR) exposure of cells
in vitro and in vivo are well documented. However, little is known about the dose-responses …

Cytogenetic dosimetry: applications in preparedness for and response to radiation emergencies

E Ainsbury, JF Barquinero, C Beinke, WF Blakely… - 2011 - elibrary.ru
Cytogenetic dosimetry is recognized as a valuable dose assessment method which fills a
gap in dosimetric technology, particularly when there are difficulties in interpreting the data …