Summary The publication of “The Sleep Apnea Syndromes” by Guilleminault et al. in the
1970s hallmarked the discovery of a new disease entity involving serious health …

Abstract Purpose of Review Given the rising prevalence of obstructive sleep apnea (OSA),
we aimed to review the epidemiologic and pathophysiologic relationship of OSA …

A organização de uma diretriz clínica é tarefa complexa, que necessariamente deve
envolver planejamento prévio, coordenação apropriada, revisão aprofundada da literatura …

Obstructive sleep apnea syndrome (OSAS) is a markedly prevalent condition across the
lifespan, particularly in overweight and obese individuals, which has been associated with …

Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …

Patients with heart failure (HF) syndromes have been categorized as those with reduced
ejection fraction (EF) or preserved EF (HFpEF), and ischemia plays a key role in both types …

Sleep disorders are highly prevalent in the general population and may be linked in a
bidirectional fashion to stroke, which is one of the leading causes of morbidity and mortality …

A organização de uma diretriz clínica é tarefa complexa, que necessariamente deve
envolver planejamento prévio, coordenação apropriada, revisão aprofundada da literatura …

Synchronization of molecular, metabolic, and cardiovascular circadian oscillations is
fundamental to human health. Sleep-disordered breathing, which disrupts such temporal …

Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …