[HTML][HTML] The urokinase plasminogen activator system in human cancers: an overview of its prognostic and predictive role

J Madunić - Thrombosis and haemostasis, 2018 - thieme-connect.com
Urokinase plasminogen activator (uPA) system regulates extracellular matrix remodelling by
activating ubiquitous protease plasmin in many important physiological processes. The …

[HTML][HTML] Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and …

P Ausina, JR Branco, TM Demaria, AM Esteves… - Scientific reports, 2020 - nature.com
Melanoma is the most aggressive and fatal type of skin cancer due to being highly
proliferative. Acetylsalicylic acid (ASA; Aspirin) and salicylic acid (SA) are ancient drugs with …

Limitations of drug concentrations used in cell culture studies for understanding clinical responses of NSAIDs

GG Graham, KF Scott - Inflammopharmacology, 2021 - Springer
In this review, the in vitro cellular effects of six nonsteroidal anti-inflammatory drugs
(NSAIDs), salicylate, ibuprofen, naproxen, indomethacin, celecoxib and diclofenac, are …

Aspirin disrupts the crosstalk of angiogenic and inflammatory cytokines between 4T1 breast cancer cells and macrophages

CC Hsieh, CH Wang - Mediators of Inflammation, 2018 - Wiley Online Library
The tumor microenvironment is rich in multiple cell types that influence tumor development.
Macrophages infiltrate tumors, where they are the most abundant immune cell population …

[HTML][HTML] Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells

TT Karalis, A Chatzopoulos, A Kondyli, AJ Aletras… - Matrix biology plus, 2020 - Elsevier
The oncogenic role of hyaluronan in several aspects of tumor biology has been well
established. Recent studies by us and others suggest that inhibition of hyaluronan synthesis …

[HTML][HTML] Metabolomics Analysis of Sodium Salicylate Improving the Preservation Quality of Ram Sperm

H Bai, Z Zhang, W Shen, Y Fu, Z Cao, Z Liu, C Yang… - Molecules, 2023 - mdpi.com
The aim of this study was to investigate the effects of sodium salicylate (SS) on the
preservation and metabolic regulation of sheep sperm. Under 4° C low-temperature …

[HTML][HTML] Zinc complex of 3, 5-di-tert-butyl salicylate inhibits viability, migration, and invasion in triple-negative breast cancer cells

H Chen, D Wang, L Fan, Z Liu, W Zhang, J Xu, Y Liu - Scientific Reports, 2022 - nature.com
Abstract The zinc complex of 3, 5-di-tert-butyl salicylate (Zn {[CH3) 3C] 2Sal} 22−) is a zinc
ion chelate of salicylate. In this study, we found that this compound inhibits viability, invasion …

[HTML][HTML] Antioxidant activity and metabolic regulation of sodium salicylate on goat sperm at low temperature

W Shen, Y Fu, H Bai, Z Zhang, Z Cao, Z Liu… - Animal …, 2024 - ncbi.nlm.nih.gov
Objective The purpose of this study was to explore the effect of sodium salicylate (SS) on
semen preservation and metabolic regulation in goats. Methods Under the condition of low …

Hydroxybenzoic Acids

D Gong, Z Zha - Handbook of Food Bioactive Ingredients: Properties …, 2023 - Springer
Nature generously offers a variety of sources like beverage crops, fruits, and vegetables rich
in hydroxybenzoic acids compounds with excellent biochemical and antioxidant capabilities …

[PDF][PDF] Priscila Ausina1, Jessica R. Branco2, Thainá M. Demaria1, Amanda M. Esteves2, João Gabriel B. Leandro1, Alan C. Ochioni2, Ana Paula M. Mendonça3 …

MF Oliveira, W Abou‑Kheir, M Sola‑Penna… - Scientific …, 2020 - odontoanamaria.com
Results Initially, the anti-cancer effects of SA and ASA on B16F10 cells, a mouse-derived
skin melanoma cell line, were evaluated in 2D and 3D cultured cells. Both, SA and ASA …