adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an evolutionarily
conserved serine/threonine kinase that was originally identified as the key player in …

Intermittent fasting is a form of time restricted eating (typically 16 h fasting and 8 h eating),
which has gained popularity in recent years and shows promise as a possible new …

Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-
19, but the mechanisms involved remain poorly understood. We carried out proteomic …

Fibrosis is a pathological result of a dysfunctional repair response to tissue injury and occurs
in a number of organs, including the lungs. Cellular metabolism regulates tissue repair and …

Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Background Neutrophil extracellular traps (NETs) have been observed in the airway in
patients with chronic obstructive pulmonary disease (COPD), but their clinical and …

Background Obesity increases both the risk of asthma and asthma severity and is a well-
known risk factor for insulin resistance and the metabolic syndrome (MS) in children and …

Resistin, a cysteine-rich protein, expressed in adipocytes, was initially proposed as a link
between obesity and diabetes in mice. In humans, resistin is considered to be a pro …

Adipose tissue is recognized as an endocrine organ that secretes bioactive substances
known as adipokines. Excess adipose tissue and adipose tissue dysfunction lead to …

Abstract The Resistin-Like Molecules (RELM) α, β, and γ and their namesake, resistin, share
structural and sequence homology but exhibit significant diversity in expression and function …