The past decade has seen the emergence of immunotherapy as a prime approach to cancer
treatment, revolutionizing the management of many types of cancer. Despite the promise of …

Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

COVID-19 shares the feature of autoantibody production with systemic autoimmune
diseases. In order to understand the role of these immune globulins in the pathogenesis of …

Glioblastoma (GBM) is the most aggressive primary malignant brain cancer and urgently
requires effective treatments. Chimeric antigen receptor T (CAR-T) cell therapy offers a …

This study identifies mechanisms mediating responses to immune checkpoint inhibitors
using mouse models of triple-negative breast cancer. By creating new mammary tumor …

Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the
formation of occlusive or rupture-prone lesions in large arteries. Complications of …

Chemokines and cytokines are critical for initiating and coordinating the organized and
sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected …

Inflammation is an important process of human healing response, wherein the tissues
respond to injuries induced by many agents including pathogens. It is characterized by pain …

The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …