Synaptic activity imposes large energy demands that are met by local adenosine
triphosphate (ATP) synthesis through glycolysis and mitochondrial oxidative …

Mitochondria are renowned for their central bioenergetic role in eukaryotic cells, where they
act as powerhouses to generate adenosine triphosphate from oxidation of nutrients. At the …

Mitochondria are essential organelles for neuronal growth, survival, and function. Neurons
use specialized mechanisms to drive mitochondria transport and to anchor them in axons …

Parkinson's disease (PD) is marked by the gradual degeneration of dopaminergic neurons
and the intracellular build-up of Lewy bodies rich in α-synuclein protein. This impairs various …

Cell migration is a complex behavior involving many energy-expensive biochemical events
that iteratively alter cell shape and location. Mitochondria, the principal producers of cellular …

Although neuronal regeneration is a highly energy-demanding process, axonal
mitochondrial transport progressively declines with maturation. Mature neurons typically fail …

Mitochondria are cellular power plants that supply ATP to power various biological activities
essential for neuronal growth, survival, and function. Due to unique morphological features …

Mitochondria are key cellular power plants essential for neuronal growth, survival, function,
and regeneration after injury. Given their unique morphological features, neurons face …

Mitochondria are dynamic organelles that undergo transport, fission, and fusion. The three
main functions of mitochondria are to generate ATP, buffer cytosolic calcium, and generate …

Mitochondria are organelles responsible for bioenergetic metabolism, calcium homeostasis,
and signal transmission essential for neurons due to their high energy consumption …