Characterizing the physiological response of bacterial cells to antibiotic treatment is crucial
for the design of antibacterial therapies and for understanding the mechanisms of antibiotic …

Streptococcus pneumoniae (S. pneumoniae) is a bacterial species often associated with the
occurrence of community-acquired pneumonia (CAP). CAP refers to a specific kind of …

Bacteria evolve resistance to antibiotics by a multitude of mechanisms. A central, yet
unsolved question is how resistance evolution affects cell growth at different drug levels …

Bacteria have evolved to develop multiple strategies for antibiotic resistance by effectively
reducing intracellular antibiotic concentrations or antibiotic binding affinities, but the role of …

Fitness effects of mutations depend on environmental parameters. For example, mutations
that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the …

Antimicrobial resistance is a worldwide health problem that demands alternative
antibacterial strategies. Modified nano-composites can be an effective strategy as compared …

Multi-drug resistance in Salmonella Typhi remains a public health concern globally. This
study aimed to investigate the function of quinolone resistance determining region (QRDR) …

Salmonella enterica is comprised of genetically distinct 'serovars' that together provide an
intriguing model for exploring the genetic basis of pathogen evolution. Although the …

Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often
characterized by noneven surfaces. However, the impact of surface irregularities on the …

Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions
via changes in cell morphologies and macromolecular composition. How bacterial …