Preterm births are a global health priority that affects 15 million babies every year worldwide.
There are no effective prognostic and therapeutic strategies relating to preterm delivery, but …

Chemotherapy is still the first line of treatment for most cancer patients. Patients receiving
chemotherapy are generally prone to infections, which result in complications, such as …

The gut microbiota has been linked to many cancers, yet its role in acute myeloid leukaemia
(AML) progression remains unclear. Here, we show decreased diversity in the gut …

Background The magnitude of microbiota perturbations after exposure to antibiotics varies
among individuals. It has been suggested that the composition of pre-treatment microbiota …

Irinotecan (CPT11) and its active metabolite ethyl-10-hydroxy-camptothecin (SN38) are
broad-spectrum cytotoxic anticancer agents. Both cause cell death in rapidly dividing cells …

L-Citrulline is a non-essential but still important amino acid that is released from enterocytes.
Because plasma levels are reduced in case of impaired intestinal function, it has become a …

Benzene is a group I carcinogen determined by IARC. The prevalence of benzene in
occupational and general environments increases the risk of acute myeloid leukemia (AML) …

Despite ongoing breakthroughs in novel anticancer therapies, chemotherapy remains a
mainstream therapeutic modality in different types of cancer. Unfortunately, chemotherapy …

High-dose chemotherapy causes intestinal inflammation and subsequent breakdown of the
mucosal barrier, permitting translocation of enteric pathogens, clinically manifesting as fever …

Background Chemotherapy is well documented to disrupt the gut microbiome, leading to
poor treatment outcomes and a heightened risk of adverse toxicity. Although strong …