Maintenance of cerebral blood vessel integrity and regulation of cerebral blood flow ensure
proper brain function. The adult human brain represents only a small portion of the body …

Objectives Limited cohort studies have assessed the association between uncontrolled pain
and risk for behavioral and psychological symptoms of dementia (BPSDs). We conducted a …

Mechanisms underlying cerebrovascular stroke outcomes are poorly understood, and the
effects of biological sex on cerebrovascular regulation post-stroke have yet to be fully …

Background This study evaluated the association between age, sex, comorbidities,
cognition, and administration of opioids with pain and the impact of all of these variables …

Untreated pain in people with Alzheimer's disease continues to be a serious public health
problem. Pain is a subjective and complex experience that becomes increasingly …

Background: Pain continues to be underrecognized and undertreated in Alzheimer's
disease (AD) while existing guidance about pain assessment and management in dementia …

Background: Sex differences in pain have been shown to exist in older adults with normal
cognition and people with Alzheimer's disease. It is unknown if sex differences in pain in …

The neurobiological underpinnings of gender differences in pain perception, and how these
differences may be modified by age, are incompletely understood, placing patients at risk of …

Alzheimer's disease or a related dementia (ADRD) disproportionately affects women with
two-thirds of individuals with ADRD comprised of women. This study examined gender …

Background There is currently no gold standard instrument for assessing pain in severely
cognitively impaired adults who are unable to provide self-report. Aims To determine …