[HTML][HTML] Circular RNAs: new layer of complexity evading breast cancer heterogeneity
A Dawoud, ZI Zakaria, HH Rashwan… - Non-Coding RNA …, 2023 - Elsevier
Advances in high-throughput sequencing techniques and bioinformatic analysis have
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …
Circular RNAs as potential biomarkers in breast cancer
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …
management of this disease depends on imaging together with immunohistochemical and …
Current therapeutic approaches and promising perspectives of using bioengineered peptides in fighting chemoresistance in triple-negative breast cancer
Breast cancer is a collation of malignancies that manifest in the mammary glands at the early
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …
Circular RNAs: biology and clinical significance of breast cancer
Z Wang, H Deng, Y Jin, M Luo, J Huang, J Wang… - RNA biology, 2023 - Taylor & Francis
Circular RNAs (circRNAs) are novel noncoding RNAs with covalently closed-loop structures
that can regulate eukaryotic gene expression. Due to their stable structure, circRNAs are …
that can regulate eukaryotic gene expression. Due to their stable structure, circRNAs are …
Investigation of BRCAness associated miRNA-gene axes in breast cancer: cell-free miR-182-5p as a potential expression signature of BRCAness
F Darbeheshti, S Kadkhoda, M Keshavarz-Fathi, S Razi… - BMC cancer, 2022 - Springer
The concept of the 'BRCAness' phenotype implies the properties that some sporadic breast
cancers (BC) share with BRCA1/2-mutation carriers with hereditary BC. Breast tumors with …
cancers (BC) share with BRCA1/2-mutation carriers with hereditary BC. Breast tumors with …
Unraveling Biomarker Signatures in Triple-Negative Breast Cancer: A Systematic Review for Targeted Approaches
P Pastena, H Perera, A Martinino, W Kartsonis… - International Journal of …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast
cancer, marked by poor outcomes and dismal prognosis. Due to the absence of targetable …
cancer, marked by poor outcomes and dismal prognosis. Due to the absence of targetable …
[HTML][HTML] Circular RNAs in and out of cells: therapeutic usages of circular RNAs
M Ju, D Kim, G Son, J Han - Molecules and cells, 2023 - Elsevier
RNAs are versatile molecules that are primarily involved in gene regulation and can thus be
widely used to advance the fields of therapeutics and diagnostics. In particular, circular …
widely used to advance the fields of therapeutics and diagnostics. In particular, circular …
Prospect of exosomal circular RNAs in breast Cancer: presents and future
Implementing precision oncology for breast cancer (BC) is a critical method for improving
patient outcomes, which relies on the use of reliable biomarkers to be effective and safe …
patient outcomes, which relies on the use of reliable biomarkers to be effective and safe …
Evaluation of circ_0000977-mediated regulatory network in breast cancer: A potential discriminative biomarker for triple-negative tumors
Previous investigations have revealed that circular RNAs (circRNAs) play pivotal roles in
cancer development and progression by participating in several biological procedures, such …
cancer development and progression by participating in several biological procedures, such …
Exploiting Long Non-Coding RNAs and Circular RNAs as Pharmacological Targets in Triple-Negative Breast Cancer Treatment
AC Palcau, R Brandi, NH Mehterov, C Botti, G Blandino… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer accounts for 15–20% of breast tumors. It is a
very aggressive and heterogeneous disease characterized by the absence of druggable …
very aggressive and heterogeneous disease characterized by the absence of druggable …