Antibiotic resistance is one of the greatest challenges of our time. This global health problem
originated from a paucity of truly effective antibiotic classes and an increased incidence of …

Therapeutic antibody technology heavily dominates the biologics market and continues to
present as a significant industrial interest in developing novel and improved antibody …

Involvement of multiple stakeholders in healthcare industry, even the simple healthcare
problems become complex due to classical approach to treatment. In the Covid-19 era …

Highlights•Computational tools for the guided design of novel antibiotics.•The importance of
biological descriptors and computational biology for the development of enhanced …

Novel insecticidal targets are always in demand due to the development of resistance. Of
Hex1, a β-N-acetyl-d-hexosaminidase identified in Ostrinia furnacalis (Asian corn borer), is …

Phytoene desaturase (PDS) is not only an important enzyme in the biosynthesis of
carotenoids but also a promising target for herbicide discovery. However, in recent years, no …

The effective clinical use of the three generation platinum anticancer drugs, cisplatin,
carboplatin, and oxaliplatin, has sparked interest in metallodrugs; however, drug resistance …

The emergence of Multidrug Resistance (MDR) strains of bacteria has accelerated the
search for new antibacterials. The specific bacterial peptidoglycan biosynthetic pathway …

Protein–protein interactions (PPIs) outnumber proteins and are crucial to many fundamental
processes; in consequence, PPIs are associated with several pathological conditions …

Artificial intelligence (AI) as a technology concept is making a major impact on a wide range
of industries and sectors. This is largely attributed to technical advancements in machine …