Architecture and dynamics of meiotic chromosomes

SN Ur, KD Corbett - Annual Review of Genetics, 2021 - annualreviews.org
The specialized two-stage meiotic cell division program halves a cell's chromosome
complement in preparation for sexual reproduction. This reduction in ploidy requires that in …

[HTML][HTML] Meiosis in polyploids and implications for genetic mapping: a review

NR Soares, M Mollinari, GK Oliveira, GS Pereira… - Genes, 2021 - mdpi.com
Plant cytogenetic studies have provided essential knowledge on chromosome behavior
during meiosis, contributing to our understanding of this complex process. In this review, we …

ZYP1 is required for obligate cross-over formation and cross-over interference in Arabidopsis

MG France, J Enderle, S Röhrig… - Proceedings of the …, 2021 - National Acad Sciences
The synaptonemal complex is a tripartite proteinaceous ultrastructure that forms between
homologous chromosomes during prophase I of meiosis in the majority of eukaryotes. It is …

[HTML][HTML] A conserved filamentous assembly underlies the structure of the meiotic chromosome axis

AMV West, SC Rosenberg, SN Ur, MK Lehmer, Q Ye… - Elife, 2019 - elifesciences.org
The meiotic chromosome axis plays key roles in meiotic chromosome organization and
recombination, yet the underlying protein components of this structure are highly diverged …

Conservation and divergence of meiotic DNA double strand break forming mechanisms in Arabidopsis thaliana

N Vrielynck, K Schneider, M Rodriguez… - Nucleic acids …, 2021 - academic.oup.com
In the current meiotic recombination initiation model, the SPO11 catalytic subunits associate
with MTOPVIB to form a Topoisomerase VI-like complex that generates DNA double strand …

ASY1 acts as a dosage-dependent antagonist of telomere-led recombination and mediates crossover interference in Arabidopsis

C Lambing, PC Kuo, AJ Tock… - Proceedings of the …, 2020 - National Acad Sciences
During meiosis, interhomolog recombination produces crossovers and noncrossovers to
create genetic diversity. Meiotic recombination frequency varies at multiple scales, with high …

Interacting genomic landscapes of REC8-cohesin, chromatin, and meiotic recombination in Arabidopsis

C Lambing, AJ Tock, SD Topp, K Choi, PC Kuo… - The plant …, 2020 - academic.oup.com
Meiosis recombines genetic variation and influences eukaryote genome evolution. During
meiosis, DNA double-strand breaks (DSBs) enter interhomolog repair to yield crossovers …

Crossover-active regions of the wheat genome are distinguished by DMC1, the chromosome axis, H3K27me3, and signatures of adaptation

AJ Tock, DM Holland, W Jiang, K Osman… - Genome …, 2021 - genome.cshlp.org
The hexaploid bread wheat genome comprises over 16 gigabases of sequence across 21
chromosomes. Meiotic crossovers are highly polarized along the chromosomes, with …

A major quantitative trait locus on chromosome A9, BnaPh1, controls homoeologous recombination in Brassica napus

EE Higgins, EC Howell, SJ Armstrong… - New …, 2021 - Wiley Online Library
Ensuring faithful homologous recombination in allopolyploids is essential to maintain
optimal fertility of the species. Variation in the ability to control aberrant pairing between …

TurboID-based proteomic profiling of meiotic chromosome axes in Arabidopsis thaliana

C Feng, E Roitinger, O Hudecz, M Cuacos, J Lorenz… - Nature plants, 2023 - nature.com
During meiotic prophase I, sister chromatids are arranged in a loop-base array along a
proteinaceous structure, called the meiotic chromosome axis. This structure is essential for …