Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Phenomena such as placebo analgesia or pain relief through distraction highlight the
powerful influence cognitive processes and learning mechanisms have on the way we …

Nerve injury leads to chronic pain and exaggerated sensitivity to gentle touch (allodynia) as
well as a loss of sensation in the areas in which injured and non-injured nerves come …

The mammalian nervous system encodes many different forms of pain, from those that arise
as a result of short-term low-grade interactions with noxious thermal, chemical, or …

The multimodal properties of the human somatosensory system continue to be unravelled.
There is mounting evidence that one of these submodalities—touch—has another …

Sensory neurons are distinguished by distinct signaling networks and receptive
characteristics. Thus, sensory neuron types can be defined by linking transcriptome-based …

Peripheral nerve injury could lead to chronic neuropathic pain. Understanding
transcriptional changes induced by nerve injury could provide fundamental insights into the …

Inflammation is a defence response to tissue damage that requires tight regulation in order
to prevent impaired healing. Tissue-resident macrophages have a key role in tissue repair …

Persistent mechanical hypersensitivity that occurs in the setting of injury or disease remains
a major clinical problem largely because the underlying neural circuitry is still not known …

Pleasurable touch is paramount during social behavior, including sexual encounters.
However, the identity and precise role of sensory neurons that transduce sexual touch …