[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

[HTML][HTML] Mechanisms underlying sonoporation: Interaction between microbubbles and cells

Y Yang, Q Li, X Guo, J Tu, D Zhang - Ultrasonics Sonochemistry, 2020 - Elsevier
The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

[HTML][HTML] Ultrasound-mediated drug delivery: sonoporation mechanisms, biophysics, and critical factors

CH YuAlfred - BME frontiers, 2022 - spj.science.org
Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …

[HTML][HTML] Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions

M Aliabouzar, OD Kripfgans, JB Fowlkes… - … für Medizinische Physik, 2023 - Elsevier
The development of phase-shift droplets has broadened the scope of ultrasound-based
biomedical applications. When subjected to sufficient acoustic pressures, the …

[HTML][HTML] Effects of medium viscoelasticity on bubble collapse strength of interacting polydisperse bubbles

D Qin, Q Zou, X Zhong, B Zhang, Z Li - Ultrasonics Sonochemistry, 2023 - Elsevier
Due to its physical and/or chemical effects, acoustic cavitation plays a crucial role in various
emerging applications ranging from advanced materials to biomedicine. The cavitation …

Landscape of cellular bioeffects triggered by ultrasound-induced sonoporation

D Przystupski, M Ussowicz - International journal of molecular sciences, 2022 - mdpi.com
Sonoporation is the process of transient pore formation in the cell membrane triggered by
ultrasound (US). Numerous studies have provided us with firm evidence that sonoporation …

[HTML][HTML] Ultrasound-responsive microbubbles and nanodroplets: A pathway to targeted drug delivery

G Shakya, M Cattaneo, G Guerriero, A Prasanna… - Advanced Drug Delivery …, 2024 - Elsevier
Ultrasound-responsive agents have shown great potential as targeted drug delivery agents,
effectively augmenting cell permeability and facilitating drug absorption. This review focuses …

Blinking acoustic nanodroplets enable fast super-resolution ultrasound imaging

F Dong, J An, J Zhang, J Yin, W Guo, D Wang, F Feng… - Acs Nano, 2021 - ACS Publications
The advent of localization-based super-resolution ultrasound (SRUS) imaging creates a
vista for precision vasculature and hemodynamic measurements in brain science …

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

ST Fateh, L Moradi, E Kohan… - Beilstein Journal of …, 2021 - beilstein-journals.org
The field of theranostics has been rapidly growing in recent years and nanotechnology has
played a major role in this growth. Nanomaterials can be constructed to respond to a variety …

[HTML][HTML] Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels

I Beekers, SAG Langeveld, B Meijlink… - Journal of Controlled …, 2022 - Elsevier
Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing
the cell membrane permeability. To aid development of a safe and effective therapeutic …