An active role for basement membrane assembly and modification in tissue sculpting

MA Morrissey, DR Sherwood - Journal of cell science, 2015 - journals.biologists.com
Basement membranes are a dense, sheet‐like form of extracellular matrix (ECM) that
underlie epithelia and endothelia, and surround muscle, fat and Schwann cells. Basement …

Extracellular interactions between fibulins and transforming growth factor (TGF)-β in physiological and pathological conditions

T Tsuda - International journal of molecular sciences, 2018 - mdpi.com
Transforming growth factor (TGF)-β is a multifunctional peptide growth factor that has a vital
role in the regulation of cell growth, differentiation, inflammation, and repair in a variety of …

[HTML][HTML] Complete cardiac regeneration in a mouse model of myocardial infarction

BJ Haubner, M Adamowicz-Brice, S Khadayate… - Aging (Albany …, 2012 - ncbi.nlm.nih.gov
Cardiac remodeling and subsequent heart failure remain critical issues after myocardial
infarction despite improved treatment and reperfusion strategies. Recently, complete cardiac …

Specific macrophage populations promote both cardiac scar deposition and subsequent resolution in adult zebrafish

L Bevan, ZW Lim, B Venkatesh, PR Riley… - Cardiovascular …, 2020 - academic.oup.com
Aims A robust inflammatory response to tissue injury is a necessary part of the repair
process but the deposition of scar tissue is a direct downstream consequence of this …

Kidney organoids recapitulate human basement membrane assembly in health and disease

MRPT Morais, P Tian, C Lawless, S Murtuza-Baker… - Elife, 2022 - elifesciences.org
Basement membranes (BMs) are complex macromolecular networks underlying all
continuous layers of cells. Essential components include collagen IV and laminins, which …

An exclusively mesodermal origin of fin mesenchyme demonstrates that zebrafish trunk neural crest does not generate ectomesenchyme

RTH Lee, EW Knapik, JP Thiery, TJ Carney - Development, 2013 - journals.biologists.com
The neural crest is a multipotent stem cell population that arises from the dorsal aspect of the
neural tube and generates both non-ectomesenchymal (melanocytes, peripheral neurons …

A median fin derived from the lateral plate mesoderm and the origin of paired fins

KW Tzung, RL Lalonde, KD Prummel… - Nature, 2023 - nature.com
The development of paired appendages was a key innovation during evolution and
facilitated the aquatic to terrestrial transition of vertebrates. Largely derived from the lateral …

An atlas of spider development at single-cell resolution provides new insights into arthropod embryogenesis

DJ Leite, A Schönauer, G Blakeley, A Harper… - EvoDevo, 2024 - Springer
Spiders are a diverse order of chelicerates that diverged from other arthropods over 500
million years ago. Research on spider embryogenesis, particularly studies using the …

Hemicentin-1 is an essential extracellular matrix component of the dermal–epidermal and myotendinous junctions

D Welcker, C Stein, NM Feitosa, J Armistead… - Scientific Reports, 2021 - nature.com
The extracellular matrix architecture is composed of supramolecular fibrillar networks that
define tissue specific cellular microenvironments. Hemicentins (Hmcn1 and Hmcn2) are …

B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes

MA Morrissey, DP Keeley, EJ Hagedorn… - Developmental cell, 2014 - cell.com
Basement membrane (BM), a sheet-like form of extracellular matrix, surrounds most tissues.
During organogenesis, specific adhesions between adjoining tissues frequently occur; …