Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress

X Wu, J Jiang, Z Gu, J Zhang, Y Chen, X Liu - Stem cell research & …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

Proangiogenic features of mesenchymal stem cells and their therapeutic applications

H Tao, Z Han, ZC Han, Z Li - Stem cells international, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) have shown their therapeutic potency for treatment of
cardiovascular diseases owing to their low immunogenicity, ease of isolation and …

Mircrining the injured heart with stem cell-derived exosomes: an emerging strategy of cell-free therapy

KH Haider, B Aramini - Stem cell research & therapy, 2020 - Springer
Bone marrow-derived mesenchymal stem cells (MSCs) have successfully progressed to
phase III clinical trials successive to an intensive in vitro and pre-clinical assessment in …

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway

X Sun, LY Huang, HX Pan, LJ Li, L Wang… - Neural regeneration …, 2023 - journals.lww.com
Although many therapeutic interventions have shown promise in treating spinal cord injury,
focusing on a single aspect of repair cannot achieve successful and functional regeneration …

Fibroblasts as a practical alternative to mesenchymal stem cells

TE Ichim, P O'Heeron, S Kesari - Journal of translational medicine, 2018 - Springer
Mesenchymal stem cell (MSC) therapy offers great potential for treatment of disease through
the multifunctional and responsive ability of these cells. In numerous contexts, MSC have …

Current status of angiogenic cell therapy and related strategies applied in critical limb ischemia

L Beltrán-Camacho, M Rojas-Torres… - International Journal of …, 2021 - mdpi.com
Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease
(PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated …

Comparative analysis of mouse bone marrow and adipose tissue mesenchymal stem cells for critical limb ischemia cell therapy

P Nammian, SL Asadi-Yousefabad, S Daneshi… - Stem Cell Research & …, 2021 - Springer
Introduction Critical limb ischemia (CLI) is the most advanced form of peripheral arterial
disease (PAD) characterized by ischemic rest pain and non-healing ulcers. Currently, the …

Overexpression of mir-135b and mir-210 in mesenchymal stromal cells for the enrichment of extracellular vesicles with angiogenic factors

JMF Vieira, LN Zamproni, CHC Wendt… - PLoS …, 2022 - journals.plos.org
Extracellular vesicles (EVs) are known as molecular carriers involved in cell communication
and the regulation of (patho) physiological processes. miRNAs and growth factors are the …

Recent developments in targets for ischemic foot disease

J Golledge, S Thanigaimani, KS Barratt… - Diabetes/Metabolism …, 2024 - Wiley Online Library
Diabetes is a key risk factor for ischaemic foot disease, which causes pain, tissue loss,
hospital admission, and major amputation. Currently, treatment focuses on …

[HTML][HTML] Strain-dependent variation in acute ischemic muscle injury

CA Schmidt, AJ Amorese, TE Ryan, EJ Goldberg… - The American journal of …, 2018 - Elsevier
Limited efficacy of clinical interventions for peripheral arterial disease necessitates a better
understanding of the environmental and genetic determinants of tissue pathology. Existing …