Complement system: promoter or suppressor of cancer progression?

M Revel, MV Daugan, C Sautés-Fridman, WH Fridman… - Antibodies, 2020 - mdpi.com
Constituent of innate immunity, complement is present in the tumor microenvironment. The
functions of complement include clearance of pathogens and maintenance of homeostasis …

GD2‐targeted immunotherapy and potential value of circulating microRNAs in neuroblastoma

S Gholamin, H Mirzaei, SM Razavi… - Journal of cellular …, 2018 - Wiley Online Library
Neuroblastoma (NB) with various clinical presentation is a known childhood malignancy.
Despite significant progress in treatment of NB afflicted patients, high risk disease is usually …

[HTML][HTML] Proteomics applications in health: biomarker and drug discovery and food industry

N Amiri-Dashatan, M Koushki… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Advancing in genome sequencing has greatly propelled the understanding of the living
world; however, it is insufficient for full description of a biological system. Focusing on …

A targeted proteomic strategy for the measurement of oral cancer candidate biomarkers in human saliva

R Kawahara, JG Bollinger, C Rivera, ACP Ribeiro… - …, 2016 - Wiley Online Library
Head and neck cancers, including oral squamous cell carcinoma (OSCC), are the sixth most
common malignancy in the world and are characterized by poor prognosis and a low …

Protein biomarker discovery studies on urinary sEV fractions separated with UF-SEC for the first diagnosis and detection of recurrence in bladder cancer patients

S Jordaens, E Oeyen, H Willems, F Ameye… - Biomolecules, 2023 - mdpi.com
Urinary extracellular vesicles (EVs) are an attractive source of bladder cancer biomarkers.
Here, a protein biomarker discovery study was performed on the protein content of small …

Complement in metastasis: a comp in the camp

D Ajona, S Ortiz-Espinosa, R Pio… - Frontiers in …, 2019 - frontiersin.org
The complement system represents a pillar of the innate immune response. This system,
critical for host defense against pathogens, encompasses more than 50 soluble, and …

[HTML][HTML] Preclinical Models of Neuroblastoma—Current Status and Perspectives

E Krawczyk, J Kitlińska - Cancers, 2023 - mdpi.com
Simple Summary Neuroblastoma is a pediatric tumor originating from the precursors of
sympathetic nerves. The disease is known for its high heterogeneity. Hence, developing …

An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides

M Chen, X Shi, RM Duke, CI Ruse, N Dai… - Nature …, 2017 - nature.com
A method for selective and comprehensive enrichment of N-linked glycopeptides was
developed to facilitate detection of micro-heterogeneity of N-glycosylation. The method takes …

Neuroblastoma models for insights into tumorigenesis and new therapies

S Kiyonari, K Kadomatsu - Expert opinion on drug discovery, 2015 - Taylor & Francis
Introduction: Neuroblastoma is the most common extracranial solid tumor in children. It
occurs in the adrenosympathetic lineage, which is derived from the neural crest. MYCN …

Multiplexed MRM‐based assays for the quantitation of proteins in mouse plasma and heart tissue

AJ Percy, SA Michaud, A Jardim, NJ Sinclair… - …, 2017 - Wiley Online Library
The mouse is the most commonly used laboratory animal, with more than 14 million mice
being used for research each year in North America alone. The number and diversity of …