[HTML][HTML] Beyond the channels: adhesion functions of aquaporin 0 and connexin 50 in lens development
Z Li, Y Quan, S Gu, JX Jiang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Lens, an avascular organ involved in light transmission, contains an internal micro-
circulatory system coupling ions to fluid movement, thus providing nutrients to internal lens …
circulatory system coupling ions to fluid movement, thus providing nutrients to internal lens …
Lens aquaporins function as peroxiporins to facilitate membrane transport of hydrogen peroxide
K Varadaraj, SS Kumari - Biochemical and biophysical research …, 2020 - Elsevier
High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …
[PDF][PDF] Structure and function of aquaporins: the membrane water channel proteins
Aquaporins are integral membrane proteins which are also known as water channel
proteins. They aid quick transportation of water across membranes and are important in …
proteins. They aid quick transportation of water across membranes and are important in …
Deletion of beaded filament proteins or the C-terminal end of Aquaporin 0 causes analogous abnormal distortion aberrations in mouse lens
K Varadaraj, PG FitzGerald, SS Kumari - Experimental eye research, 2021 - Elsevier
Lens-specific beaded filament (BF) proteins CP49 and filensin interact with the C-terminus of
the water channel protein Aquaporin 0 (AQP0). Previously we have reported that a C …
the water channel protein Aquaporin 0 (AQP0). Previously we have reported that a C …
[HTML][HTML] C-terminal end of Aquaporin 0 regulates lens gap junction channel function
K Varadaraj, J Gao, RT Mathias… - … Ophthalmology & Visual …, 2019 - tvst.arvojournals.org
Purpose: We reported previously that aquaporin 0 (AQP0) modulates lens fiber cell gap
junction (GJ) channel function. The present study was conducted to find out whether the C …
junction (GJ) channel function. The present study was conducted to find out whether the C …
Biology of the transparent lens and changes with age
JI Clark - Albert and Jakobiec's Principles and Practice of …, 2022 - Springer
From the perspectives of molecular embryology, physiology, metabolism, and biophysics,
there is much to learn from the lens about vision health and aging. The unique coordination …
there is much to learn from the lens about vision health and aging. The unique coordination …
Positively charged amino acid residues in the extracellular loops A and C of lens aquaporin 0 interact with the negative charges in the plasma membrane to facilitate …
S Kumari, G Taginik, S Varadaraj, K Varadaraj - Experimental eye research, 2019 - Elsevier
This investigation was undertaken to find out whether the positive charges in the
Extracellular Loops A (ELA) and C (ELC) of Aquaporin 0 (AQP0) are involved in lens fiber …
Extracellular Loops A (ELA) and C (ELC) of Aquaporin 0 (AQP0) are involved in lens fiber …
Deletion of beaded filament proteins or the C-terminal end of Aquaporin 0 causes analogous abnormal distortion aberrations in mouse lens.
S Kumari, K Varadaraj, P Fitzgerald - 2021 - escholarship.org
Lens-specific beaded filament (BF) proteins CP49 and filensin interact with the C-terminus of
the water channel protein Aquaporin 0 (AQP0). Previously we have reported that a C …
the water channel protein Aquaporin 0 (AQP0). Previously we have reported that a C …