Ellagitannins (ETs) and ellagic acid (EA) are dietary polyphenols poorly absorbed but
extensively metabolized by the human gut microbiota to produce different urolithins (Uros) …

A large number of epidemiological studies have shown that consumption of fruits,
vegetables, and beverages rich in (poly) phenols promote numerous health benefits from …

Coffee is a Rubiaceae coffee plant ranked as the first of the three most important beverages
in the world, with effects including lowering blood sugar, protecting the liver, and protecting …

Background Natural polyphenols provide numerous human-health promoting benefits,
including gut microbiota regulation, microbial composition changes, and improvement of …

We aimed to elucidate the gut bacteria that characterize the human urolithin metabotypes A
and B (UM-A and UM-B). We report here a new bacterium isolated from the feces of a …

Abstract The Aryl Hydrocarbon Receptor (AHR) is a ligand-dependent transcription factor
able to control complex transcriptional processes in several cell types, which has been …

Urolithins, metabolites produced by the gut microbiota from the polyphenols ellagitannins
and ellagic acid, are discovered by the research group in humans almost 20 years ago …

Urolithin (Uro) B is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranates …

Highlights•Latest studies on interindividual variability in health effects of polyphenols.•The
role of gene polymorphisms is worth further study.•Identification of microbial metabolic …

The gut microbiota (GM) produces different polyphenol-derived metabolites, yielding high
interindividual variability and hampering consistent health effects. GM metabotypes …