Parasitic protozoa of the genus Leishmania have provided a useful perspective for
immunologists in terms of host defense mechanisms critical for the resolution of infection …

Protozoan parasites belonging to the genus Leishmania exhibit a pronounced tropism for
macrophages although they have the capacity to infect a variety of other phagocytic and non …

Reactivation of dormant infections causes an immense burden of morbidity and mortality in
the world at large. Reactivation can occur as a result of immunosuppression, environmental …

Polyamines (PAs) are essential metabolites in eukaryotes, participating in a variety of
proliferative processes, and in trypanosomatid protozoa play an additional role in the …

Leishmania spp. are sandfly-transmitted parasitic protozoa that cause a spectrum of
important diseases and lifelong chronic infections in humans. In the mammalian host, these …

Leishmaniasis is a vector-borne disease found in many countries worldwide. The causative
agent of the disease, Leishmania spp., lives as an obligate intracellular parasite within …

Cutaneous leishmaniasis affects millions of people around the world. Several species of
Leishmania infect mouse strains, and murine models closely reproduce the cutaneous …

The requirements for effective and efficient intracellular killing of Leishmania amazonensis
by activated macrophages are unknown. Despite resistance to the arginase inhibitor LOHA …

Leishmaniasis is a complex disease that is caused by parasites of the Leishmania genus.
Leishmania are further classified into several complexes, each of which can engage in …

We have evaluated levels of 6 cytokines in sera of 35 patients of kala azar (KA), 29 post kala
azar dermal leishmaniasis (PKDL), and 18 healthy controls using cytometric bead array …