[HTML][HTML] Long COVID: pathophysiological factors and abnormalities of coagulation

S Turner, MA Khan, D Putrino, A Woodcock… - Trends in Endocrinology …, 2023 - cell.com
Acute COVID-19 infection is followed by prolonged symptoms in approximately one in ten
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …

The machinery of exosomes: biogenesis, release, and uptake

SV Krylova, D Feng - International Journal of Molecular Sciences, 2023 - mdpi.com
Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are
secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA …

[HTML][HTML] Long COVID: the nature of thrombotic sequelae determines the necessity of early anticoagulation

C Wang, C Yu, H Jing, X Wu, VA Novakovic… - Frontiers in Cellular …, 2022 - frontiersin.org
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life
leading to an increased burden on the healthcare system, their families and society at large …

Laboratory findings and biomarkers in Long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery

B Zhao, H Lin, X Jiang, W Li, Y Gao, M Li, Y Yu… - …, 2024 - pmc.ncbi.nlm.nih.gov
Over the past ten years, significant advancements have been made in exploring plant-
derived exosome-like nanoparticles (PELNs) for disease therapeutics and drug delivery …

Exosome-and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders

B Lu, J Ku, R Flojo, C Olson, D Bengford… - Advanced Drug Delivery …, 2022 - Elsevier
Cell-generated extracellular vesicles (EVs) are being engineered as biologically-inspired
vehicles for targeted delivery of therapeutic agents to treat difficult-to-manage human …

Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia

Y Lim, HY Kim, D Han, BK Choi - Journal of Extracellular …, 2023 - Wiley Online Library
Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in
subgingival plaque and is associated with systemic inflammatory diseases. Extracellular …

COVID-19 inflammation and implications in drug delivery

M Zoulikha, F Huang, Z Wu, W He - Journal of Controlled Release, 2022 - Elsevier
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …

COVID infection in 4 steps: Thermodynamic considerations reveal how viral mucosal diffusion, target receptor affinity and furin cleavage act in concert to drive the …

M Popovic, JH Martin, RJ Head - Heliyon, 2023 - cell.com
We have developed a mechanistic model of SARS-CoV-2 and SARS-CoV infection,
exploring the relationship between the viral diffusion in the mucosa and viral affinity for the …

Exosomal circRNA RHOT1 promotes breast cancer progression by targeting miR-204-5p/PRMT5 axis

W Jiang, YP Yu, J Ou, Y Li, N Zhu - Cancer Cell International, 2023 - Springer
Abstract Background Circular RNA RHOT1 (circRHOT1) plays crucial roles in tumorigenesis
by competing with microRNAs. It is largely abundant in tumor cell-derived exosomes …