Peripheral nerve injury induced changes in the spinal cord and strategies to counteract/enhance the changes to promote nerve regeneration
Y Liu, H Wang - Neural regeneration research, 2020 - journals.lww.com
Peripheral nerve injury leads to morphological, molecular and gene expression changes in
the spinal cord and dorsal root ganglia, some of which have positive impact on the survival …
the spinal cord and dorsal root ganglia, some of which have positive impact on the survival …
The mechanisms of peripheral nerve preconditioning injury on promoting axonal regeneration
X Yang, R Liu, Y Xu, XY Ma, B Zhou - Neural Plasticity, 2021 - Wiley Online Library
Two major factors contribute to the failure of axonal regrowth in the central nervous system
(CNS), namely, the neuronal intrinsic regenerative capacity and the extrinsic local inhibitory …
(CNS), namely, the neuronal intrinsic regenerative capacity and the extrinsic local inhibitory …
The conditioning lesion response in dorsal root ganglion neurons is inhibited in oncomodulin knock-out mice
Regeneration can occur in peripheral neurons after injury, but the mechanisms involved are
not fully delineated. Macrophages in dorsal root ganglia (DRGs) are involved in the …
not fully delineated. Macrophages in dorsal root ganglia (DRGs) are involved in the …
Effects of endogenous inflammation signals elicited by nerve growth factor, interferon-γ, and interleukin-4 on peripheral nerve regeneration
Background Large gap healing is a difficult issue in the recovery of peripheral nerve injury.
The present study provides in vivo trials of silicone rubber chambers filled with collagen …
The present study provides in vivo trials of silicone rubber chambers filled with collagen …
Toll-like receptor 9-mediated neuronal innate immune reaction is associated with initiating a pro-regenerative state in neurons of the dorsal root ganglia non …
P Dubový, I Hradilová-Svíženská, V Brázda… - International Journal of …, 2021 - mdpi.com
One of the changes brought about by Wallerian degeneration distal to nerve injury is
disintegration of axonal mitochondria and consequent leakage of mitochondrial DNA …
disintegration of axonal mitochondria and consequent leakage of mitochondrial DNA …
Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush
Injuries within the peripheral nervous system (PNS) lead to sensory and motor deficits, as
well as neuropathic pain, which strongly impair the life quality of patients. Although most …
well as neuropathic pain, which strongly impair the life quality of patients. Although most …
[HTML][HTML] The Intrinsic Neuronal Activation of the CXCR4 Signaling Axis Is Associated with a Pro-Regenerative State in Cervical Primary Sensory Neurons Conditioned …
P Dubový, I Hradilová-Svíženská, V Brázda… - International Journal of …, 2024 - mdpi.com
CXCL12 and CXCR4 proteins and mRNAs were monitored in the dorsal root ganglia
(DRGs) of lumbar (L4–L5) and cervical (C7–C8) spinal segments of naïve rats, rats …
(DRGs) of lumbar (L4–L5) and cervical (C7–C8) spinal segments of naïve rats, rats …
Interleukin-6 contributes to initiation of neuronal regeneration program in the remote dorsal root ganglia neurons after sciatic nerve injury
P Dubový, I Hradilová-Svíženská, I Klusáková… - Histochemistry and Cell …, 2019 - Springer
To assess the potential role of IL-6 in sciatic nerve injury-induced activation of a pro-
regenerative state in remote dorsal root ganglia (DRG) neurons, we compared protein levels …
regenerative state in remote dorsal root ganglia (DRG) neurons, we compared protein levels …
Expression of thioredoxin‐1 in the ASJ neuron corresponds with and enhances intrinsic regenerative capacity under lesion conditioning in C. elegans
NWF Grooms, MQ Fitzgerald, B Zuckerman… - FEBS …, 2023 - Wiley Online Library
A conditioning lesion of the peripheral sensory axon triggers robust central axon
regeneration in mammals. We trigger conditioned regeneration in the Caenorhabditis …
regeneration in mammals. We trigger conditioned regeneration in the Caenorhabditis …
[HTML][HTML] Valproate attenuates somatic hyperalgesia induced by orofacial inflammation combined with stress through inhibiting spinal IL-6 and STAT1 phosphorylation
CX Xu, XY Qiu, Y Guo, TM Xu, RJ Traub, HN Feng… - Brain research …, 2024 - Elsevier
Temporomandibular disorder (TMD) and fibromyalgia syndrome (FMS) may present as
comorbid conditions, but treatment options are ineffective. The purpose of this study was to …
comorbid conditions, but treatment options are ineffective. The purpose of this study was to …