Machine learning for brain age prediction: Introduction to methods and clinical applications

L Baecker, R Garcia-Dias, S Vieira, C Scarpazza… - …, 2021 - thelancet.com
The rise of machine learning has unlocked new ways of analysing structural neuroimaging
data, including brain age prediction. In this state-of-the-art review, we provide an …

Predicting age using neuroimaging: innovative brain ageing biomarkers

JH Cole, K Franke - Trends in neurosciences, 2017 - cell.com
The brain changes as we age and these changes are associated with functional
deterioration and neurodegenerative disease. It is vital that we better understand individual …

Machine learning applications in epilepsy

B Abbasi, DM Goldenholz - Epilepsia, 2019 - Wiley Online Library
Abstract Machine learning leverages statistical and computer science principles to develop
algorithms capable of improving performance through interpretation of data rather than …

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

JH Cole, RPK Poudel, D Tsagkrasoulis, MWA Caan… - NeuroImage, 2017 - Elsevier
Abstract Machine learning analysis of neuroimaging data can accurately predict
chronological age in healthy people. Deviations from healthy brain ageing have been …

Brain age and other bodily 'ages': implications for neuropsychiatry

JH Cole, RE Marioni, SE Harris, IJ Deary - Molecular psychiatry, 2019 - nature.com
As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

The burden of epilepsy and unmet need in people with focal seizures

P Ioannou, DL Foster, JW Sander, S Dupont… - Brain and …, 2022 - Wiley Online Library
Background Epilepsy is one of the most common neurological conditions worldwide. As a
chronic condition, epilepsy imposes a significant burden on people with epilepsy and …

Mind the gap: Performance metric evaluation in brain‐age prediction

AMG de Lange, M Anatürk, J Rokicki… - Human Brain …, 2022 - Wiley Online Library
Estimating age based on neuroimaging‐derived data has become a popular approach to
developing markers for brain integrity and health. While a variety of machine‐learning …

[HTML][HTML] Accurate brain‐age models for routine clinical MRI examinations

DA Wood, S Kafiabadi, A Al Busaidi, E Guilhem… - Neuroimage, 2022 - Elsevier
Convolutional neural networks (CNN) can accurately predict chronological age in healthy
individuals from structural MRI brain scans. Potentially, these models could be applied …

Factors associated with brain ageing-a systematic review

J Wrigglesworth, P Ward, IH Harding, D Nilaweera… - BMC neurology, 2021 - Springer
Background Brain age is a biomarker that predicts chronological age using neuroimaging
features. Deviations of this predicted age from chronological age is considered a sign of age …

Longitudinal assessment of multiple sclerosis with the brain‐age paradigm

JH Cole, J Raffel, T Friede, A Eshaghi… - Annals of …, 2020 - Wiley Online Library
Objective During the natural course of multiple sclerosis (MS), the brain is exposed to aging
as well as disease effects. Brain aging can be modeled statistically; the so‐called “brain …