Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …

Purpose The purpose of this study was to evaluate the efficiency of biologic augmentation of
rotator cuff repair with iliac crest bone marrow-derived mesenchymal stem cells (MSCs). The …

The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Mesenchymal stromal/stem cells (MSC) are promising candidates for cellular therapy of
different diseases in humans and in animals. Following the guidelines of the International …

Due to their unique hierarchical structure and composition, tendons possess characteristic
biomechanical properties, including high mechanical strength and viscoelasticity, which …

Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …

Background Hypercholesterolemia increases the risk of tendon pain and tendon rupture.
Tendon-derived stem cells (TDSCs) play a vital role in the development of tendinopathy. Our …

Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …