Introduction Over the last 20 years (2000-2019) the partners of the Global Polio Eradication
Initiative (GPEI) invested in the development and application of mathematical models of …

Identity, and Sexual Orientation, 2 was requested by the National Institutes of Health (NIH) in
the USA to examine SOGISC measurement for surveys in research, administrative, and …

Although there have been no cases of serotype 2 wild poliovirus for more than 20 years,
transmission of serotype 2 vaccine-derived poliovirus (VDPV2) and associated paralytic …

Comment 714 www. thelancet. com Vol 400 September 3, 2022 risk of vaccine-associated
paralytic poliomyelitis caused by Sabin 2. 6 Although most countries eliminated Sabinlike …

Enormous progress has been made in global efforts to eradicate poliovirus, using live-
attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to …

The live-attenuated oral poliovirus vaccine (OPV or Sabin vaccine) replicates in gut-
associated tissues, eliciting mucosa and systemic immunity. OPV protects from disease and …

Delays in achieving the global eradication of wild poliovirus transmission continue to
postpone subsequent cessation of all oral poliovirus vaccine (OPV) use. Countries must stop …

Background Sabin strains used in oral poliovirus vaccines (OPV) can revert to virulence and,
in rare instances, cause disease or generate vaccine-derived strains leading to outbreaks in …

Polio and enterovirus surveillance may include a number of approaches, including
incidence-based observation, a sentinel physician system, environmental monitoring and …

Precise diagnosis and treatment of tumors currently still face considerable challenges due to
the development of highly degreed heterogeneity in the dynamic evolution of tumors. With …