Vitamin D supplementation can prevent and cure nutritional rickets in infants and children.
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …

Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

Aims Low vitamin D status is associated with a higher risk for cardiovascular diseases
(CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null …

The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Background This paper reports results from the 5th International Conference “Controversies
in Vitamin D” that was held in Stresa, Italy, 15–18 September 2021. The conference is part of …

Background Observational studies have demonstrated an association between decreased
vitamin D level and risk of multiple sclerosis (MS); however, it remains unclear whether this …

Background Low vitamin D status is often associated with systemic low-grade inflammation
as reflected by elevated C-reactive protein (CRP) levels. We investigated the causality and …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

The prevalence of hypovitaminosis D has risen in developed countries over the past few
years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D …

Vitamin D is a precursor of the steroid hormone calcitriol that is crucial for bone and mineral
metabolism. Both the high prevalence of vitamin D deficiency in the general population and …