[HTML][HTML] Lipid droplet biogenesis and functions in health and disease

A Zadoorian, X Du, H Yang - Nature Reviews Endocrinology, 2023 - nature.com
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control

G Chen, JL Harwood, MJ Lemieux, SJ Stone… - Progress in Lipid …, 2022 - Elsevier
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

[HTML][HTML] Lipid Production from Nannochloropsis

XN Ma, TP Chen, B Yang, J Liu, F Chen - Marine drugs, 2016 - mdpi.com
Microalgae are sunlight-driven green cell factories for the production of potential bioactive
products and biofuels. Nannochloropsis represents a genus of marine microalgae with high …

Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production

M Tai, G Stephanopoulos - Metabolic engineering, 2013 - Elsevier
Microbial oil production by heterotrophic organisms is a promising path for the cost-effective
production of biofuels from renewable resources provided high conversion yields can be …

Yeast lipid metabolism at a glance

L Klug, G Daum - FEMS yeast research, 2014 - academic.oup.com
During the last decades, lipids have gained much attention due to their involvement in
health and disease. Lipids are required for the formation of membranes and contribute to …

[HTML][HTML] Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

CLE Yen, SJ Stone, S Koliwad, C Harris… - Journal of lipid …, 2008 - Elsevier
Triacylglycerols (triglycerides)(TGs) are the major storage molecules of metabolic energy
and FAs in most living organisms. Excessive accumulation of TGs, however, is associated …

Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae

SA Henry, SD Kohlwein, GM Carman - Genetics, 2012 - academic.oup.com
Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …

Yarrowia lipolytica as a model for bio-oil production

A Beopoulos, J Cescut, R Haddouche… - Progress in lipid …, 2009 - Elsevier
The yeast Yarrowialipolytica has developed very efficient mechanisms for breaking down
and using hydrophobic substrates. It is considered an oleaginous yeast, based on its ability …

Advancing oleaginous microorganisms to produce lipid via metabolic engineering technology

MH Liang, JG Jiang - Progress in lipid research, 2013 - Elsevier
With the depletion of global petroleum and its increasing price, biodiesel has been
becoming one of the most promising biofuels for global fuels market. Researchers exploit …

[HTML][HTML] Compartmentation of triacylglycerol accumulation in plants

KD Chapman, JB Ohlrogge - Journal of Biological Chemistry, 2012 - ASBMB
Triacylglycerols from plants, familiar to most people as vegetable oils, supply 25% of dietary
calories to the developed world and are increasingly a source for renewable biomaterials …