Interfaces, the boundary that separates two or more chemical compositions and/or phases of
matter, alters basic chemical and physical properties including the thermodynamics of …

The IQ Consortium reports on the current state of process analytical technology (PAT) for
active pharmaceutical ingredient (API) development in branded pharmaceutical companies …

The multiphase nature of slurries can make them difficult to process and monitor in real time.
For example, the nuclear waste slurries present at the Hanford site in Washington State are …

As a traditional linear regression model, the partial least squares (PLS) could not handle the
nonlinearities in spectral quantitative analysis. This paper focuses on four types of nonlinear …

Modeling chemical reaction systems is an important but complex task. The identified kinetic
model must be able to explain all the underlying rate processes such as chemical reactions …

Kinetic modeling of batch reactions monitored by in situ spectroscopy has been shown to be
a helpful method for developing a complete understanding of reaction systems. Much work …

In this paper, we proposed a wavelength selection method based on random decision
particle swarm optimization with attractor for near‐infrared (NIR) spectra quantitative …

Paul Gemperline has been active in many areas of data analysis in chemistry. In this
contribution, we build on his developments in advanced process analysis. The most …

Cultivation of mammalian cells for the generation of therapeutics requires the use of cell
culture media which is a defined mixture of nutrients including carbohydrates, amino acids …

Primarily undergraduate institutions (PUIs) are a unique training ground for young scientists
who work closely with faculty on their research. Researchers at PUIs face a number of …