Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration
Perturbations in iron homeostasis and iron accumulation feature in several
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …
[HTML][HTML] The pathological role of ferroptosis in ischemia/reperfusion-related injury
Abstract Ischemia/reperfusion (I/R) is a pathological process that occurs in numerous organs
throughout the human body, and it is frequently associated with severe cellular damage and …
throughout the human body, and it is frequently associated with severe cellular damage and …
LncRNA PVT1 regulates ferroptosis through miR-214-mediated TFR1 and p53
J Lu, F Xu, H Lu - Life sciences, 2020 - Elsevier
Aim The study aims to investigate the roles of LncRNA and miRNA in ferroptosis in brain
ischemia/reperfusion (I/R) in vivo and in vitro. Materials and methods qPCR assay was used …
ischemia/reperfusion (I/R) in vivo and in vitro. Materials and methods qPCR assay was used …
Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
Functional failure of tau contributes to age-dependent, iron-mediated neurotoxicity, and as
iron accumulates in ischemic stroke tissue, we hypothesized that tau failure may exaggerate …
iron accumulates in ischemic stroke tissue, we hypothesized that tau failure may exaggerate …
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
P Wang, Y Cui, Q Ren, B Yan, Y Zhao, P Yu… - Cell death & …, 2021 - nature.com
Ischaemic stroke is becoming the most common cerebral disease in aging populations, but
the underlying molecular mechanism of the disease has not yet been fully elucidated …
the underlying molecular mechanism of the disease has not yet been fully elucidated …
Iron, ferroptosis, and ischemic stroke
Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …
Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential
R She, D Liu, J Liao, G Wang, J Ge… - Frontiers in Cellular …, 2023 - frontiersin.org
Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
[HTML][HTML] A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein
Inflammation is associated with a number of chronic conditions, such as cancer and
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …
Targeting ferroptosis as a promising therapeutic strategy for ischemia-reperfusion injury
Y Pan, X Wang, X Liu, L Shen, Q Chen, Q Shu - Antioxidants, 2022 - mdpi.com
Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …
contributes to pathological damage in various conditions, including ischemic stroke …
Ferroptosis and its multifaceted roles in cerebral stroke
Y Zhang, X Lu, B Tai, W Li, T Li - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Ferroptosis is a unique regulated cell death defined by the intracellular iron overload and
distinct biological features compared with other well-known programmed cell death …
distinct biological features compared with other well-known programmed cell death …