Microbial Peptidyl-Prolyl cis/trans Isomerases (PPIases): Virulence Factors and Potential Alternative Drug Targets
CM Ünal, M Steinert - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Initially discovered in the context of immunomodulation, peptidyl-prolyl cis/trans isomerases
(PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at …
(PPIases) were soon identified as enzymes catalyzing the rate-limiting protein folding step at …
A druggable secretory protein maturase of Toxoplasma essential for invasion and egress
SK Dogga, B Mukherjee, D Jacot, T Kockmann… - Elife, 2017 - elifesciences.org
Micronemes and rhoptries are specialized secretory organelles that deploy their contents at
the apical tip of apicomplexan parasites in a regulated manner. The secretory proteins …
the apical tip of apicomplexan parasites in a regulated manner. The secretory proteins …
Research advances in interactions related to Toxoplasma gondii microneme proteins
Q Liu, FC Li, CX Zhou, XQ Zhu - Experimental parasitology, 2017 - Elsevier
Toxoplasma gondii microneme proteins (TgMICs), secreted by micronemes upon contact
with host cells, are reported to play important roles in multiple stages of the T. gondii life …
with host cells, are reported to play important roles in multiple stages of the T. gondii life …
Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain
Following each round of replication, daughter merozoites of the malaria parasite
Plasmodium falciparum escape (egress) from the infected host red blood cell (RBC) by …
Plasmodium falciparum escape (egress) from the infected host red blood cell (RBC) by …
The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin
C Withers-Martinez, M Strath, F Hackett… - Nature …, 2014 - nature.com
Malaria is caused by a protozoan parasite that replicates within an intraerythrocytic
parasitophorous vacuole. Release (egress) of malaria merozoites from the host erythrocyte …
parasitophorous vacuole. Release (egress) of malaria merozoites from the host erythrocyte …
Maturation of subtilisin-like protease NbSLP1 from microsporidia Nosema bombycis
R Wang, Q Li, F Liu, X Dang, Q Sun… - Frontiers in Cellular …, 2022 - frontiersin.org
Microsporidia are obligate intracellular parasites and possess a unique way of invading
hosts, namely germination. Microsporidia are able to infect almost all animal cells by …
hosts, namely germination. Microsporidia are able to infect almost all animal cells by …
[PDF][PDF] Review on diagnosis and molecular characterization of Toxoplasma gondii in humans and animals.
Toxoplasma gondii is an obligate intracellular protozoon which causes toxoplasmosis, an
important zoonotic disease that is endemic worldwide. Common sources of T. gondii …
important zoonotic disease that is endemic worldwide. Common sources of T. gondii …
Identification and Molecular Characterization of Microneme 5 of Eimeria acervulina
ZC Zhang, JW Huang, MH Li, YX Sui, S Wang, LR Liu… - PLoS …, 2014 - journals.plos.org
In the present study, the microneme 5 gene of Eimeria acervulina (E. acervulina)(EaMIC5)
was cloned and characterized. Specific primers for the rapid amplification of cDNA ends …
was cloned and characterized. Specific primers for the rapid amplification of cDNA ends …
An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in …
LB Thornton, P Teehan, K Floyd, C Cochrane… - PLoS …, 2019 - journals.plos.org
Toxoplasma gondii is an apicomplexan parasite with the ability to use foodborne, zoonotic,
and congenital routes of transmission that causes severe disease in immunocompromised …
and congenital routes of transmission that causes severe disease in immunocompromised …
Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress
M Martinez, A Bouillon, S Brûlé, B Raynal, A Haouz… - Mbio, 2024 - Am Soc Microbiol
Malaria symptoms are associated with the asexual multiplication of Plasmodium falciparum
within human red blood cells (RBCs) and fever peaks coincide with the egress of daughter …
within human red blood cells (RBCs) and fever peaks coincide with the egress of daughter …