Epigenetics in Disease Prevention and Mitigation Epigenetics is the regulation of gene
expression through alterations in DNA or associated factors (other than the DNA sequence) …

This year is the tenth anniversary of the publication in this journal of a model suggesting the
existence of'tumour progenitor genes'. These genes are epigenetically disrupted at the …

Beckwith-Wiedemann syndrome (BWS), a human genomic imprinting disorder, is
characterized by phenotypic variability that might include overgrowth, macroglossia …

LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

Epigenetic control of gene transcription is critical for normal human development and
cellular differentiation. While alterations of epigenetic marks such as DNA methylation have …

Since its discovery in 1983, the epigenetics of human cancer has been in the shadows of
human cancer genetics. But this area has become increasingly visible with a growing …

Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Chromosome abnormalities have been known for over 50 years, though the methods of
analysis have become increasing more sophisticated and precise. Surprisingly, the …

It is becoming clear that epigenetic changes are involved in human disease as well as
during normal development. A unifying theme of disease epigenetics is defects in …