Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae

M Rozwandowicz, MSM Brouwer… - Journal of …, 2018 - academic.oup.com
Bacterial antimicrobial resistance (AMR) is constantly evolving and horizontal gene transfer
through plasmids plays a major role. The identification of plasmid characteristics and their …

Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids

S Redondo-Salvo, R Fernández-López, R Ruiz… - Nature …, 2020 - nature.com
Plasmids can mediate horizontal gene transfer of antibiotic resistance, virulence genes, and
other adaptive factors across bacterial populations. Here, we analyze genomic composition …

PlasmidFinder and in silico pMLST: identification and typing of plasmid replicons in whole-genome sequencing (WGS)

A Carattoli, H Hasman - Horizontal gene transfer: methods and protocols, 2020 - Springer
PlasmidFinder and in silico plasmid multiLocus sequence typing (pMLST) are two easy-to-
use web tools for detection and characterization of plasmid sequences in whole-genome …

In Silico Detection and Typing of Plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing

A Carattoli, E Zankari, A García-Fernández… - Antimicrobial agents …, 2014 - Am Soc Microbiol
In the work presented here, we designed and developed two easy-to-use Web tools for in
silico detection and characterization of whole-genome sequence (WGS) and whole-plasmid …

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

[HTML][HTML] Current epidemiology and growing resistance of gram-negative pathogens

DM Livermore - The Korean journal of internal medicine, 2012 - ncbi.nlm.nih.gov
In the 1980s, Gram-negative pathogens appeared to have been beaten by oxyimino-
cephalosporins, carbapenems, and fluoroquinolones. Yet these pathogens have fought …

Universal whole-sequence-based plasmid typing and its utility to prediction of host range and epidemiological surveillance

J Robertson, K Bessonov, J Schonfeld… - Microbial …, 2020 - microbiologyresearch.org
Bacterial plasmids play a large role in allowing bacteria to adapt to changing environments
and can pose a significant risk to human health if they confer virulence and antimicrobial …

Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae

S Conlan, PJ Thomas, C Deming, M Park… - Science translational …, 2014 - science.org
Public health officials have raised concerns that plasmid transfer between
Enterobacteriaceae species may spread resistance to carbapenems, an antibiotic class of …

Plasmid classification in an era of whole-genome sequencing: application in studies of antibiotic resistance epidemiology

A Orlek, N Stoesser, MF Anjum, M Doumith… - Frontiers in …, 2017 - frontiersin.org
Plasmids are extra-chromosomal genetic elements ubiquitous in bacteria, and commonly
transmissible between host cells. Their genomes include variable repertoires of 'accessory …