Type 2 diabetes
Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes
worldwide. The number affected is increasing rapidly with alarming trends in children and …
worldwide. The number affected is increasing rapidly with alarming trends in children and …
Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …
populations have an underlying predisposition to deficient insulin secretion, which has a key …
Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes
ATN Nair, A Wesolowska-Andersen, C Brorsson… - Nature Medicine, 2022 - nature.com
Abstract Type 2 diabetes (T2D) is a complex chronic disease characterized by considerable
phenotypic heterogeneity. In this study, we applied a reverse graph embedding method to …
phenotypic heterogeneity. In this study, we applied a reverse graph embedding method to …
Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using …
Background Research using data-driven cluster analysis has proposed five subgroups of
diabetes with differences in diabetes progression and risk of complications. We aimed to …
diabetes with differences in diabetes progression and risk of complications. We aimed to …
The triglyceride-glucose index is a predictor for cardiovascular and all-cause mortality in CVD patients with diabetes or pre-diabetes: evidence from NHANES 2001 …
Q Zhang, S Xiao, X Jiao, Y Shen - Cardiovascular diabetology, 2023 - Springer
Background The association between the triglyceride-glucose (TyG) index and mortality in
cardiovascular disease (CVD) patients with diabetes or pre-diabetes remains unclear. This …
cardiovascular disease (CVD) patients with diabetes or pre-diabetes remains unclear. This …
Subtypes of type 2 diabetes determined from clinical parameters
Type 2 diabetes (T2D) is defined by a single metabolite, glucose, but is increasingly
recognized as a highly heterogeneous disease, including individuals with varying clinical …
recognized as a highly heterogeneous disease, including individuals with varying clinical …
A novel diabetes typology: towards precision diabetology from pathogenesis to treatment
C Herder, M Roden - Diabetologia, 2022 - Springer
The current classification of diabetes, based on hyperglycaemia, islet-directed antibodies
and some insufficiently defined clinical features, does not reflect differences in aetiological …
and some insufficiently defined clinical features, does not reflect differences in aetiological …
Precision subclassification of type 2 diabetes: a systematic review
Background Heterogeneity in type 2 diabetes presentation and progression suggests that
precision medicine interventions could improve clinical outcomes. We undertook a …
precision medicine interventions could improve clinical outcomes. We undertook a …
Current insights and emerging trends in early-onset type 2 diabetes
Type 2 diabetes diagnosed in childhood or early adulthood is termed early-onset type 2
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …
[HTML][HTML] ADA/EASD precision medicine in diabetes initiative: an international perspective and future vision for precision medicine in diabetes
JJ Nolan, AR Kahkoska, Z Semnani-Azad… - Diabetes …, 2022 - ncbi.nlm.nih.gov
The Precision Medicine in Diabetes Initiative (PMDI) was launched in 2018 by the American
Diabetes Association (ADA) in collaboration with the European Association for the Study of …
Diabetes Association (ADA) in collaboration with the European Association for the Study of …