Defensins: The natural peptide antibiotic
Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …
Mucin dynamics and enteric pathogens
MA McGuckin, SK Lindén, P Sutton… - Nature Reviews …, 2011 - nature.com
The extracellular secreted mucus and the cell surface glycocalyx prevent infection by the
vast numbers of microorganisms that live in the healthy gut. Mucin glycoproteins are the …
vast numbers of microorganisms that live in the healthy gut. Mucin glycoproteins are the …
Mechanistic landscape of membrane-permeabilizing peptides
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
Cathelicidins: family of antimicrobial peptides. A review
Cathelicidins are small, cationic, antimicrobial peptides found in humans and other species,
including farm animals (cattle, horses, pigs, sheep, goats, chickens, rabbits and in some …
including farm animals (cattle, horses, pigs, sheep, goats, chickens, rabbits and in some …
Obesity‑a risk factor for increased COVID‑19 prevalence, severity and lethality
D Petrakis, D Margină… - Molecular …, 2020 - spandidos-publications.com
Abstract Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are a group of
viruses that cause infections in the human respiratory tract, which can be characterized …
viruses that cause infections in the human respiratory tract, which can be characterized …
[图书][B] Theory of Molecular Fluids: Volume 2: Applications
CG Gray, KE Gubbins, CG Joslin - 2011 - books.google.com
Existing texts on the statistical mechanics of liquids treat only spherical molecules. However,
nearly all fluids of practical interest are composed of non-spherical molecules that are often …
nearly all fluids of practical interest are composed of non-spherical molecules that are often …
Antimicrobial peptides: general overview and clinical implications in human health and disease
E Guaní-Guerra, T Santos-Mendoza, SO Lugo-Reyes… - Clinical …, 2010 - Elsevier
Antimicrobial peptides (AMPs) are evolutionarily conserved molecules involved in the
defense mechanisms of a wide range of organisms. Produced in bacteria, insects, plants …
defense mechanisms of a wide range of organisms. Produced in bacteria, insects, plants …
Isolation and characterization of human μ-Defensin-3, a novel human inducible peptide antibiotic
J Harder, J Bartels, E Christophers… - Journal of Biological …, 2001 - ASBMB
The growing public health problem of infections caused by multiresistant Gram-positive
bacteria, in particularStaphylococcus aureus, prompted us to screen human epithelia for …
bacteria, in particularStaphylococcus aureus, prompted us to screen human epithelia for …
Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils
J Turner, Y Cho, NN Dinh, AJ Waring… - Antimicrobial agents …, 1998 - Am Soc Microbiol
Human neutrophils contain two structurally distinct types of antimicrobial peptides, β-sheet
defensins (HNP-1 to HNP-4) and the α-helical peptide LL-37. We used radial diffusion …
defensins (HNP-1 to HNP-4) and the α-helical peptide LL-37. We used radial diffusion …
Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37
The influence of ion composition, pH, and peptide concentration on the conformation and
activity of the 37-residue human antibacterial peptide LL-37 has been studied. At micromolar …
activity of the 37-residue human antibacterial peptide LL-37 has been studied. At micromolar …