Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme catalyzing the crosslinking
between Gln and Lys residues and involved in various pathophysiological events. Besides …

Accumulation of unwanted/misfolded proteins in aggregates has been observed in airways
of patients with cystic fibrosis (CF), a life-threatening genetic disorder caused by mutations in …

Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …

Transglutaminase 2 (TG2) is the most widely distributed member of the transglutaminase
family with almost all cell types in the body expressing TG2 to varying extents. In addition to …

Tissue transglutaminase (TG2) is a widely distributed multifunctional protein involved in a
broad range of cellular and metabolic functions carried out in a variety of cellular …

Abstract Transglutaminase 2 (TG2) is primarily known as the most ubiquitously expressed
member of the transglutaminase family with Ca 2+-dependent protein crosslinking activity; …

Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by
genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine …

Reactive oxygen species, ROS, are regulators of endothelial cell migration, proliferation and
survival, events critically involved in angiogenesis. Different isoforms of ROS-generating …

The cystic fibrosis transmembrane regulator protein (CFTR) is an ion channel in the apical
surface of epithelial membranes that regulates other ion channels. Dysfunction of CFTR …