Zeta potential of extracellular vesicles: toward understanding the attributes that determine colloidal stability

G Midekessa, K Godakumara, J Ord, J Viil… - ACS …, 2020 - ACS Publications
Extracellular vesicles (EVs), including exosomes and microvesicles (< 200 nm), play a vital
role in intercellular communication and carry a net negative surface charge under …

The role of extracellular vesicles in embryo implantation

K Chen, J Liang, T Qin, Y Zhang, X Chen… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are membrane-coating nanoparticles derived from cells. The
effect of cell-to-cell communication mediated by EVs has been investigated in different fields …

Promoting roles of embryonic signals in embryo implantation and placentation in cooperation with endocrine and immune systems

H Fujiwara, M Ono, Y Sato, K Imakawa, T Iizuka… - International Journal of …, 2020 - mdpi.com
Embryo implantation in the uterus is an essential process for successful pregnancy in
mammals. In general, the endocrine system induces sufficient embryo receptivity in the …

Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal …

K Godakumara, J Ord, F Lättekivi… - Reproductive Biology …, 2021 - Springer
Background The period of time when the embryo and the endometrium undergo significant
morphological alterations to facilitate a successful implantation—known as “window of …

Rapid generation of functional nanovesicles from human trophectodermal cells for embryo attachment and outgrowth

QH Poh, A Rai, M Pangestu, LA Salamonsen… - …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are important mediators of embryo attachment and outgrowth
critical for successful implantation. While EVs have garnered immense interest in their …

Omics insights into extracellular vesicles in embryo implantation and their therapeutic utility

QH Poh, A Rai, LA Salamonsen, DW Greening - Proteomics, 2023 - Wiley Online Library
Implantation success relies on intricate interplay between the developing embryo and the
maternal endometrium. Extracellular vesicles (EVs) represent an important player of this …

Proteome reprogramming of endometrial epithelial cells by human trophectodermal small extracellular vesicles reveals key insights into embryo implantation

QH Poh, A Rai, II Carmichael, LA Salamonsen… - …, 2021 - Wiley Online Library
Embryo implantation into the receptive endometrium is critical in pregnancy establishment,
initially requiring reciprocal signalling between outer layer of the blastocyst (trophectoderm …

Role of extracellular vesicles in intercellular communication during reproduction

K Godakumara, K Dissanayake… - … in Domestic Animals, 2022 - Wiley Online Library
The mammalian reproduction is a process of controlled cellular growth and development
regulated by constant communication between the gametes, the subsequent embryo and …

Secretory proteomic responses of endometrial epithelial cells to trophoblast-derived extracellular vesicles

S Muhandiram, K Dissanayake, T Orro… - International Journal of …, 2023 - mdpi.com
Synchronized crosstalk between the embryo and endometrium during the periconception
period is integral to pregnancy establishment. Increasing evidence suggests that the …

The extracellular vesicles proteome of endometrial cells simulating the receptive menstrual phase differs from that of endometrial cells simulating the non-receptive …

AR Hart, NLA Khan, K Dissanayake, K Godakumara… - Biomolecules, 2023 - mdpi.com
Successful embryo implantation into a receptive endometrium requires mutual endometrial-
embryo communication. Recently, the function of extracellular vehicles (EVs) in cell-to-cell …