It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder of the central
nervous system (CNS) and one of the leading causes of neurological deficits and disability …

Progressive loss of dopaminergic neurons in the substantia nigra pars compacta and their
terminal connections in the striatum are central features in Parkinson's disease (PD) …

Experimental autoimmune encephalomyelitis (EAE) is still the most widely accepted animal
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …

The dysregulation of inflammatory responses and of immune self-tolerance is considered to
be a key element in the autoreactive immune response in multiple sclerosis (MS) …

T cell activation is an energy-demanding process fueled by increased glucose consumption
and accompanied by upregulation of the insulin receptor (INSR). In this article, we report that …

The role of T regulatory (Treg) cells expressing the forkhead box transcription factor 3
(foxp3) in the control of autoaggressive immune responses is the subject of intense …

Demyelination due to autoreactive T cells and inflammation in the central nervous system
are principal features of multiple sclerosis (MS), a chronic and highly disabling human …

Recent evidence has shown that neuroinflammation plays a key role in the pathogenesis of
Parkinson's disease (PD). However, different components of the brain's immune system may …

Multiple sclerosis (MS) is an autoimmune disorder causing demyelination and
neurodegeneration in the central nervous system. MS is characterized by disturbed motor …