Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

The preproglucagon gene (Gcg) is expressed by specific enteroendocrine cells (L-cells) of
the intestinal mucosa, pancreatic islet α-cells, and a discrete set of neurons within the …

More than 20 years ago, Pories et al. published a seminal article,“Who Would Have Thought
It? An Operation Proves to Be the Most Effective Therapy for Adult-Onset Diabetes Mellitus.” …

Представлен 3-ий пересмотр клинических рекомендаций по лечению морбидного
ожирения у взрослых. Морбидным называется ожирение с индексом массы тела …

Background For patients with obesity and type 2 diabetes, weight loss improves insulin
sensitivity and β-cell function, and can induce remission of diabetes. The comparative …

Although promising therapeutics are in the pipeline, bariatric surgery (also known as
metabolic surgery) remains our most effective strategy for the treatment of obesity and type 2 …

Context Hypoglycemia, occurring after bariatric and other forms of upper gastrointestinal
surgery, is increasingly encountered by clinical endocrinologists. The true frequency of this …

Objective: The aim is to provide guidelines for the evaluation and management of adults with
hypoglycemic disorders, including those with diabetes mellitus. Evidence: Using the …

Postprandial glucose, together with related hyperinsulinemia and lipidaemia, has been
implicated in the development of chronic metabolic diseases like obesity, type 2 diabetes …

Context: Gastric bypass surgery (GBP) results in rapid weight loss, improvement of type 2
diabetes (T2DM), and increase in incretins levels. Diet-induced weight loss also improves …