Environmental research and public health in the 21st century face serious challenges such
as increased air pollution and global warming, widespread use of potentially harmful …

The GRCh37. p13 primary assembly of the human genome contains 20805 protein coding
mRNA, and 37147 non-protein coding genes and pseudogenes that as a result of RNA …

MicroRNAs are endogenous posttranscriptional modulators that negatively control the
expression of their target genes and play an important role in the development and …

Background Hepatocellular carcinoma (HCC) is one of the most deadly cancer worldwide.
Multiple long noncoding RNAs (lncRNAs) are recently identified as crucial oncogenic factors …

We aimed to identify microRNA (miRNA) expression patterns in the serum of prostate cancer
(CaP) patients that predict the risk of early treatment failure following radical prostatectomy …

Following the elucidation of the human genome and components of the epigenome, it is
timely to revisit what is known of vitamin D receptor (VDR) function. Early transcriptomic …

Defining patient-to-patient similarity is essential for the development of precision medicine in
clinical care and research. Conceptually, the identification of similar patient cohorts appears …

Due to its extraordinary heterogeneity and complexity, cancer is often proposed as a model
case of a systems biology disease or network disease. There is a critical need of effective …

Epigenetic modifiers play important roles in fine-tuning the cellular transcriptome. Any
imbalance in these processes may lead to abnormal transcriptional activity and thus result in …

Oral squamous cell carcinoma (OSCC) of the tongue is a common type of head and neck
malignancy with a poor prognosis, underscoring the urgency for early detection. MicroRNAs …