Applications of nanodosimetry in particle therapy planning and beyond
This topical review summarizes underlying concepts of nanodosimetry. It describes the
development and current status of nanodosimetric detector technology. It also gives an …
development and current status of nanodosimetric detector technology. It also gives an …
Orally bioavailable and blood–brain barrier-penetrating ATM inhibitor (AZ32) radiosensitizes intracranial gliomas in mice
J Karlin, J Allen, SF Ahmad, G Hughes… - Molecular cancer …, 2018 - AACR
Inhibition of ataxia-telangiectasia mutated (ATM) during radiotherapy of glioblastoma
multiforme (GBM) may improve tumor control by short-circuiting the response to radiation …
multiforme (GBM) may improve tumor control by short-circuiting the response to radiation …
[HTML][HTML] Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end …
Mutations in the breast cancer susceptibility 1 (BRCA1) gene are catalysts for breast and
ovarian cancers. Most mutations are associated with the BRCA1 N-and C-terminal domains …
ovarian cancers. Most mutations are associated with the BRCA1 N-and C-terminal domains …
DNA damage response in human stem cells and neural descendants
Glial cells are crucial for the normal function of neurons and are intricately involved in the
pathogenesis of neurodegenerative diseases as well as neurologic malignancies. A deeper …
pathogenesis of neurodegenerative diseases as well as neurologic malignancies. A deeper …
From Harmony to Dissonance: An organoid-based study of chromosomal instability and aneuploidy in colorectal cancer progression
RH van Jaarsveld - 2019 - pure.knaw.nl
The development of colorectal cancer (CRC) is associated with the accumulation of genetic
mutations that provide cells with malignant properties. Cancer cells carry defects in genome …
mutations that provide cells with malignant properties. Cancer cells carry defects in genome …
Recent Patents on Morphometric Analysis of Eukaryotic Cells
M Manssur Bueno e Silva… - Recent Patents on …, 2013 - ingentaconnect.com
Eukaryotic cells are complex structures formed by several compartments. They present
dynamic morphometry and functions, which are assessed in basic cell research to elucidate …
dynamic morphometry and functions, which are assessed in basic cell research to elucidate …