[HTML][HTML] Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
Sex differences in traumatic brain injury: what we know and what we should know
There is growing recognition of the problem of male bias in neuroscience research,
including in the field of traumatic brain injury (TBI) where fewer women than men are …
including in the field of traumatic brain injury (TBI) where fewer women than men are …
[HTML][HTML] Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
Background Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …
Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits
Chronic neuroinflammation with sustained microglial activation occurs following severe
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …
[HTML][HTML] Microglial activation in traumatic brain injury
CK Donat, G Scott, SM Gentleman… - Frontiers in aging …, 2017 - frontiersin.org
Microglia have a variety of functions in the brain, including synaptic pruning, CNS repair and
mediating the immune response against peripheral infection. Microglia rapidly become …
mediating the immune response against peripheral infection. Microglia rapidly become …
Animal models of traumatic brain injury
Y Xiong, A Mahmood, M Chopp - Nature Reviews Neuroscience, 2013 - nature.com
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …
[HTML][HTML] Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …
Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities
D Lozano, GS Gonzales-Portillo, S Acosta… - Neuropsychiatric …, 2015 - Taylor & Francis
Traumatic brain injury (TBI) is a serious public health problem accounting for 1.4 million
emergency room visits by US citizens each year. Although TBI has been traditionally …
emergency room visits by US citizens each year. Although TBI has been traditionally …
[HTML][HTML] Very early administration of progesterone for acute traumatic brain injury
DW Wright, SD Yeatts, R Silbergleit… - … England Journal of …, 2014 - Mass Medical Soc
Background Traumatic brain injury (TBI) is a major cause of death and disability worldwide.
Progesterone has been shown to improve neurologic outcome in multiple experimental …
Progesterone has been shown to improve neurologic outcome in multiple experimental …
Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes
HM Bramlett, WD Dietrich - Journal of neurotrauma, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …
successfully translated to the clinic. Increased importance on the progressive, long-term …