Endocannabinoid system: chemical characteristics and biological activity

B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

The evolving culture of medical cannabis in Canada for the management of chronic pain

H Clarke, M Fitzcharles - Frontiers in Pharmacology, 2023 - frontiersin.org
Although used therapeutically for millennia, cannabis has been a prohibited substance
worldwide for most of the 20th Century. With revision of prohibitive regulations in many …

Cannabidiol interacts antagonistically with cisplatin and additively with mitoxantrone in various melanoma cell lines—An isobolographic analysis

P Marzęda, P Wróblewska-Łuczka, M Drozd… - International Journal of …, 2022 - mdpi.com
The medical application of cannabidiol (CBD) has been gathering increasing attention in
recent years. This non-psychotropic cannabis-derived compound possesses antiepileptic …

Anti-inflammatory effects of cannabigerol in rheumatoid arthritis synovial fibroblasts and peripheral blood mononuclear cell cultures are partly mediated by TRPA1

T Lowin, MS Tigges-Perez, E Constant… - International Journal of …, 2023 - mdpi.com
Since its medical legalization, cannabis preparations containing the major
phytocannabinoids (cannabidiol (CBD) and δ9-tetrahydrocannabinol (THC)) have been …

[HTML][HTML] Cannabinoids in anesthesia and chronic pain: Where do we stand?

K Pandey, W Hoda - Saudi Journal of Anaesthesia, 2024 - journals.lww.com
Cannabis derivatives have been conventionally employed globally for their curative and
restorative properties for various ailments. However, its recreational use and consequent …

Full-Spectrum Cannabidiol for Treating Chronic Temporomandibular Arthralgia: A Case Report

JPC Tanganeli, MDS Tanganeli… - Integrative Medicine …, 2023 - liebertpub.com
Introduction: Temporomandibular disorders (TMDs) are public health problem that can
considerably affect quality of life. In particular, chronic situations are a challenge for the …