Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

Injuries to the musculoskeletal system are common, debilitating and expensive. In many
cases, healing is imperfect, which leads to chronic impairment. Gene transfer might improve …

At present, bone nonunion and delayed union are still difficult problems in orthopaedics.
Since the discovery of bone morphogenetic protein (BMP), it has been widely used in …

Tendon tissue engineering with a biomaterial scaffold that mimics the tendon extracellular
matrix (ECM) and is biomechanically suitable, and when combined with readily available …

Musculoskeletal diseases are one of the leading causes of disability worldwide. Among
them, tendon and ligament injuries represent an important aspect to consider in both …

Rupture of the anterior cruciate ligament (ACL) is one of the most common ligamentous
injuries of the knee. Limitations of allografts and autografts in ACL reconstruction as well as …

Tendons and ligaments (T/L) are dense connective tissues of mesodermal origin. During
embryonic development, the tendon-specific cells descend from a sub-set of mesenchymal …

Mohawk homeobox (MKX) has been demonstrated as a tendon/ligament specific
transcription factor. The aim of this study was to investigate the role of MKX in …

Tendons and ligaments provide connections between muscle and bone or bone and bone
to enable locomotion. Damage to tendons and ligaments caused by acute or chronic injury …

Management of anterior cruciate ligament (ACL) tears has continuously evolved since its
first description in approximately 170 AD by Claudius Galenus of Pergamum and Rome. The …