Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Exosomes have emerged as critical mediators of intercellular communication, both locally
and systemically, by regulating a diverse range of biological processes between cells …

Mesenchymal stem/stromal cells (MSCs) have been demonstrated to hold great potential for
the treatment of several diseases. Their therapeutic effects are largely mediated by …

During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …

Microvesicles (MVs) are subcellular physiological vehicles present in all body fluids that
mediate the transfer of intercellular information within biological systems and contribute to …

We previously demonstrated that multipotent mesenchymal stromal cells (MSCs) that
overexpress microRNA 133b (miR-133b) significantly improve functional recovery in rats …

The accumulation of extracellular β-amyloid (Aβ) plaques within the brain is unique to
Alzheimer's disease (AD) and thought to induce synaptic deficits and neuronal loss. Optimal …

Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …

Circular RNAs (circRNAs) are a novel class of endogenous non-coding RNAs characterized
by a covalently closed-loop structure generated through a special type of alternative splicing …

Metabolic syndrome defines a cluster of interrelated risk factors for cardiovascular disease
and diabetes mellitus. These factors include metabolic abnormalities, such as …