The mitral valve (MV) is the left atrioventricular heart valve that regulates blood flow between
the left atrium and left ventricle (LV) during the cardiac cycle. Contrary to the aortic valve …

The tricuspid valve ensures unidirectional blood flow from the right atrium to the right
ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear …

Ischemic mitral regurgitation (IMR) is a prevalent cardiac disease associated with substantial
morbidity and mortality. Contemporary surgical treatments continue to have limited long-term …

Valve interstitial cells (VIC) are the primary cell type residing within heart valve tissues. In
many valve pathologies, VICs become activated and will subsequently profoundly remodel …

The clinical benefit of patient-specific modeling of heart valve disease remains an
unrealized goal, often a result of our limited understanding of the in vivo milieu. This is …

Aortic valves (AVs) undergo unique stretch histories that include high rates and magnitudes.
While major differences in deformation patterns have been observed between normal and …

Retinal detachment occurs when liquid slips behind the retina and does not allow the latter
to lay flat on the posterior region of the eye. It alters the vision of the patient, hence requiring …