This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …

Several current immunotherapy approaches target private neoantigens derived from
mutations that are unique to individual patients' tumors. However, immunotherapeutic …

Induced pluripotent stem cells (iPSCs) have strong potential in regenerative medicine
applications; however, immune rejection caused by HLA mismatching is a concern. B2M …

Mutations in the RAS oncogenes occur in multiple cancers, and ways to target these
mutations has been the subject of intense research for decades. Most of these efforts are …

Therapeutic vaccines that elicit cytotoxic T cell responses targeting tumor-specific
neoantigens hold promise for providing long-term clinical benefit to patients with cancer …

Developing effective strategies to prevent or treat coronavirus disease 2019 (COVID-19)
requires understanding the natural immune response to severe acute respiratory syndrome …

The timing of SARS-CoV-2 transmission is a critical factor to understand the epidemic
trajectory and the impact of isolation, contact tracing and other non-pharmaceutical …

We have calculated six-locus high resolution HLA A∼ C∼ B∼ DRB3/4/5∼ DRB1∼ DQB1
haplotype frequencies using all Be The Match® Registry volunteer donors typed by DNA …

Fine-mapping to plausible causal variation may be more effective in multi-ancestry cohorts,
particularly in the MHC, which has population-specific structure. To enable such studies, we …

Genotyping of classical human leukocyte antigen (HLA) alleles is an essential tool in the
analysis of diseases and adverse drug reactions with associations mapping to the major …